At the scene, paramedics found one vehicle that had gone off the highway and down an embankment, with the driver trapped.
The call was escalated to a rescue, which brought a response from the White Marsh Volunteer Fire Company. Rescue crews worked to stabilize the vehicle before using the Jaws of Life and other tools to remove the patient.
Additional rescuers prepared a rope rescue system to bring the patient up the embankment, out of the woods, and back to the roadway.
The patient, a seriously-injured adult female, was taken to Shock Trauma.
Maryland State Police are investigating the cause of the collision.